Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
Light-induced giant random telegraph noise in CuScP<sub>2</sub>S<sub>6</sub>/MoS<sub>2</sub> heterostructures and their use in noise resilience image inference. [PDF]
Ghosh A +7 more
europepmc +1 more source
Space‐Time Coding Conformal Metasurfaces for Multifrequency Beam Steering and Shaping
Space‐time coding conformal metasurfaces enable dynamic wave control on curved surfaces by combining programmable spatial patterns with temporal modulation. This study shows that a single conformal aperture can independently manipulate multiple frequency components, achieving multifunctional beam shaping and steering, with implications for ...
Filippo Pepe +8 more
wiley +1 more source
Defect-Engineered VO<sub>2</sub> Films: From Abrupt Phase Transition to Continuous Infrared Modulation via High-Vacuum Annealing. [PDF]
Liu L +5 more
europepmc +1 more source
We reveal the electronic origin of hidden interfacial doping in monolayer MoS2 grown by MOCVD, identifying sulfate related and water like species as intrinsic donors. Through dry interface engineering approach, we demonstrate MOCVD‐grown single‐crystal MoS2 wafers as a transfer‐free platform for the reliable evaluation of intrinsic gate stacks and ...
Shuhong Li +12 more
wiley +1 more source
Poly(Ionic Liquids) and Ionogels for Electrochromic Devices: Material Design and Additive Manufacturing Strategies. [PDF]
Statsenko TG +3 more
europepmc +1 more source
Field‐programmed anisotropy imparts material‐level intelligence to soft composites. Magnetic torque dynamics drive magneto‐piezoelectric nanowires from random dispersion into deterministic axial alignment. The resulting hierarchical percolation networks confine electromechanical coupling to specific axes and intrinsically decouple superposed force ...
Yubin Kim +9 more
wiley +1 more source
Flexible Photodetector with Ultrahigh on/off Current Ratio Based on Monocrystal PbI<sub>2</sub> Nanosheet via Micro-Spacing In-Air Sublimation. [PDF]
Yu C, Du Q, Liu Y, Liu Y, Wang W, Qin S.
europepmc +1 more source
Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
Optical Bistability in Photonic Topological Hypercrystals and Its Applications in Photonic Neural Network. [PDF]
Li H +6 more
europepmc +1 more source

