Results 81 to 90 of about 2,228,096 (302)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

An Error Protection Protocol for user-transparent bridging of Fast Ethernet data transmission over the optical fading channel in an Aeronautical environment [PDF]

, 2008
This paper presents an extensive insight into error protection techniques for free space optical links, focusing in particular in aeronautic stratospherically applications.
Serrano-Solsona, Clara, Henniger, Hennes, Epple, Bernhard   +2 more
core  

Nanophotonic Devices for Optical Interconnect [PDF]

, 2010
We review recent progress in nanophotonic devices for compact optical interconnect networks. We focus on microdisk-laser-based transmitters and discuss improved design and advanced functionality including all-optical wavelength conversion and flip-flops.
Van Thourhout, D., Spuesens, ThijsTW05000080057130802000488975FBD436DC-F0ED-11E1-A9DE-61C894A0A6B4, Morthier, G., Roelkens, Günther, Regreny, P., Kumar, Rajesh, Kopp, Christophe, Morthier, Geert, Roelkens, GüntherTW050019970516598010016648210000-0002-4667-5092F6876ADC-F0ED-11E1-A9DE-61C894A0A6B4, Rojo-Romeo, Pedro, Rojo-Romeo, P., Spuesens, Thijs, Raz, Oded, Spuesens, T., Van Thourhout, DriesTW058010010572560000-0003-0111-431XF4F6F962-F0ED-11E1-A9DE-61C894A0A6B4, Selvaraja, shankar kumarTW05002005713557801002125771F83539B8-F0ED-11E1-A9DE-61C894A0A6B4, Roelkens, G., Van Thourhout, Dries, Liu, Liu, Morthier, GeertTW058010006923930000-0003-1819-6489F45CEBD8-F0ED-11E1-A9DE-61C894A0A6B4, Selvaraja, shankar kumar, Mandorlo, F., Kumar, RajeshUGent000081417049802000450074FB1DE3A0-F0ED-11E1-A9DE-61C894A0A6B4, Kopp, C., Liu, LiuTW05802000203736F9047232-F0ED-11E1-A9DE-61C894A0A6B4, Thourhout, Van, D., Raz, O., Selvaraja, S.K., Grenouillet, Laurent, Grenouillet, L., Mandorlo, Fabien, Kumar, R., Regreny, Philippe   +32 more
core   +2 more sources

Coverage Performance of Non-Lambertian Underwater Wireless Optical Communications for 6G Internet of Things

Inventions
In medium- and short-range underwater application scenarios, thanks to the superior performance in transmission bandwidth, link latency, and security, underwater wireless optical communication (UWOC) is growing to be a promising complement to the mature ...
Jupeng Ding, Chih-Lin I, Jintao Wang, Jian Song   +3 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Numerical simulations of beam propagation through optical turbulence for high-altitude platform crosslinks [PDF]

, 2004
In this paper we introduce a simulation method for modelling clear-air atmospheric turbulence effects for long horizontal stratospheric paths. Divergence angles of several hundred microradians in combination with link distances up to 800 km require to ...
Perlot, Nicolas, Jüngling, Ralf, Giggenbach, Dirk, Horwath, Joachim   +3 more
core  

Mitigation of Scintillation Effects in WDM FSO System using Multibeam Technique

Journal of Telecommunications and Information Technology, 2017
Free Space Optical communication (FSO) has engrossed a large section of researchers in recent times due to its wide bandwidth, effortless deployment and immune links making it appropriate for communication purposes.
Marvi Grover, Preeti Singh, Pardeep Kaur
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Transmitters and Receivers for High Capacity Indoor Optical Wireless Communication

Telecom
In this paper, we present recent advancements in transmitter and receiver technologies for Optical Wireless Communication (OWC). OWC offers very wide license-free optical spectrum which enables very high capacity transmission.
Mikolaj Wolny, Eduardo Muller, Eduward Tangdiongga   +2 more
doaj   +1 more source