Results 61 to 70 of about 192,487 (281)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Averaging out magnetic forces with fast rf-sweeps in an optical trap for metastable chromium atoms [PDF]
, 2007 We introduce a novel type of time-averaged trap, in which the internal state of the atoms is rapidly modulated to modify magnetic trapping potentials. In our experiment, fast radiofrequency (rf) linear sweeps flip the spin of atoms at a fast rate, which ...
A. Pouderous +10 more
core +2 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Orientation- and wavelength-dependent sperm motility in optical trapping
Journal of Innovative Optical Health SciencesOptical tweezers technology has the characteristics of noncontact manipulation in three dimensions and steerable separation in solutions, and could be applied to obtain a separated sperm with high quality for intracytoplasmic sperm injection (ICSI ...
Juan Wang +10 more
doaj +1 more source
Nonlinear optical properties of photoresists for projection lithography [PDF]
, 1996 Optical beams are self-focused and self-trapped upon initiating crosslinking in photoresists. This nonlinear optical phenomenon is apparent only for low average optical intensities and produces index of refraction changes as large as 0.04.
Kewitsch, Anthony S., Yariv, Amnon
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2017 We present a novel type of three-dimensional dark focus optical trapping potential for ultra-cold atoms and Bose-Einstein condensates. This 'optical bottle' is created with blue-detuned laser light exploiting the phenomenon of conical refraction ...
Ahufinger, V. +7 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Molecules, 2021 Continuous rotation of a cholesteric droplet under the heat gradient was observed by Lehmann in 1900. This phenomenon, the so-called Lehmann effect, consists of unidirectional rotation around the heat flux axis.
Jarinee Kiang-ia +5 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi +3 more
wiley +1 more source