Results 111 to 120 of about 2,721,612 (374)

Optical tweezers for drug discovery

Drug Discovery Today, 2023
The time taken and the cost of producing novel therapeutic drugs presents a significant burden - a typical target-based drug discovery process involves computational screening of drug libraries, compound assays and expensive clinical trials. This review summarises the value of dynamic conformational information obtained by optical tweezers and how this
Matthew T J, Halma, Jack A, Tuszynski, Gijs J L, Wuite   +2 more
openaire   +2 more sources

Kirigami‐Inspired Breathable Smart Contact Lens for Wireless Monitoring of Corneal Hypoxia and Microenvironment

Advanced Healthcare Materials, EarlyView.
A kirigami‐inspired breathable smart contact lens is reported for wireless monitoring of corneal hypoxia and microenvironment. The ultrathin (55 µm) and flexible sensing device enables digitalized, in situ and precise monitoring of dissolved oxygen, humidity, and temperature (R2 >0.98).
Jiaxue Zhu, Ling Yang, Qing Yang, Yin Huang, Yuhang Li, Yueqing He, Xuxu Yang, Zhiyan Yang, Yonghong Jiao, Wenbin Wei, Yihao Chen, Xue Feng   +11 more
wiley   +1 more source

Multi-frequency passive and active microrheology with optical tweezers

Scientific Reports, 2021
Optical tweezers have attracted significant attention for microrheological applications, due to the possibility of investigating viscoelastic properties in vivo which are strongly related to the health status and development of biological specimens.
Randhir Kumar, Valerio Vitali, Timo Wiedemann, Robert Meissner, Paolo Minzioni, Cornelia Denz   +5 more
doaj   +1 more source

Tilt control in optical tweezers [PDF]

Journal of Biomedical Optics, 2008
Laser trapping of micrometer-sized objects floating in water is investigated through the use of a tilted laser beam. With a change in the tilt direction, the orientation of the trapped object can be easily controlled when the object has an asymmetric body or nonuniform refractive index, such as nanowires, living cells, and so on.
Yasuyuki Kimura, Kenichi Yoshikawa, Koji Kubo, Masatoshi Ichikawa   +3 more
openaire   +3 more sources

Manipulating Ferroelectric Topological Polar Structures with Twisted Light

Advanced Materials, EarlyView.
We demonstrate dynamic control of ferroelectric order in quasi‐2D CsBiNb2O7 using twisted ultraviolet light carrying orbital angular momentum. Our approach harnesses non‐resonant multiphoton absorption and induced strain to modulate topological of ferroelectric polarization textures.
Nimish P. Nazirkar, Viet Tran, Pascal Bassène, Atoumane Ndiaye, Julie Barringer, Jie Jiang, Wonsuk Cha, Ross Harder, Jian Shi, Moussa N'Gom, Edwin Fohtung   +10 more
wiley   +1 more source

Microrheology with optical tweezers: data analysis [PDF]

, 2012
We present a data analysis procedure that provides the solution to a long-standing issue in microrheology studies, i.e. the evaluation of the fluids' linear viscoelastic properties from the analysis of a finite set of experimental data, describing (for ...
Brau R R, Evans R M L, Ferry J D, Fischer M, Jonathan M Cooper, Keen S, Kuo S, Lathi B P, Manlio Tassieri, Nicholas J Bailey, Pesce G, Pesce G, Preece D, R M L Evans, Rebecca L Warren, Starrs L, Stokes J R, Valentine M T, Valentine M T Dewalt L E Ou-Yang H D, Waigh T A, Weitz D A, Yanagishima T, Yoon Y-Z   +22 more
core   +2 more sources

Photonic nanojets in optical tweezers [PDF]

Journal of Quantitative Spectroscopy and Radiative Transfer, 2015
10th International Conference Series on Laser-Light and Interactions with Particles (Marseilles, 2014)
openaire   +3 more sources

Robust Full‐Surface Bonding of Substrate and Electrode for Ultra‐Flexible Sensor Integration

Advanced Materials, EarlyView.
A direct hybrid bonding method that enables both gold and parylene bonding without adhesives is developed. This technique achieves full‐surface direct bonding of electrodes and substrates in flexible electronic connections. The method offers high flexibility, stable mechanical durability, and high‐resolution interconnections, accommodating varying ...
Masahito Takakuwa, Daishi Inoue, Lulu Sun, Michitaka Yamamoto, Shinjiro Umezu, Daisuke Hashizume, Toshihiro Itoh, Kenjiro Fukuda, Takao Someya, Tomoyuki Yokota   +9 more
wiley   +1 more source

Feasibility of Multiple Micro-Particle Trapping—A Simulation Study

Sensors, 2015
Both optical tweezers and acoustic tweezers have been demonstrated for trapping small particles in diverse biomedical applications. Compared to the optical tweezers, acoustic tweezers have deeper penetration, lower intensity, and are more useful in light
Yanyan Yu, Weibao Qiu, Bernard Chiu, Lei Sun   +3 more
doaj   +1 more source

Direct observation of the effects of spin dependent momentum of light in optical tweezers

APL Photonics, 2020
We demonstrate that tight focusing of a circularly polarized Gaussian beam in optical tweezers leads to spin-momentum locking—with the transverse momentum density (Poynting vector) being helicity-dependent, while the transverse spin angular momentum ...
Debapriya Pal, Subhasish Dutta Gupta, Nirmalya Ghosh, Ayan Banerjee   +3 more
doaj   +1 more source