Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan +46 more
wiley +1 more source
Multiplane 2.5D microscopy for high-throughput high-resolution tissue imaging. [PDF]
J Biomed OptWang LM, Pandey D, Zhang W, Han KY.
europepmc +1 more source
Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan +12 more
wiley +1 more source
Feature-based clustering of global sea level anomaly time series. [PDF]
Sci RepSun Q, Wan J, Liu S.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo +13 more
wiley +1 more source
I. Optics of photography.—On a self-acting focus-equalizer, or the means of producing the differential movement of the two lenses of a photographic optical combination, which is capable, during the exposure, of bringing consecutively all the planes of a solid figure into focus, without altering the size of the various images superposed [PDF]
A. Claudet
openalex +1 more source
Comparative Assessment of Large Language Models in Optics and Refractive Surgery: Performance on Multiple-Choice Questions. [PDF]
Vision (Basel)Attal L +4 more
europepmc +1 more source
Adaptive optics for high-resolution imaging
Nature Reviews Methods Primers, 2021 K. Hampson +6 more
semanticscholar +1 more source