Results 161 to 170 of about 18,411,493 (260)
Sufficient statistics in the optimum control of stochastic systems
Charlotte Striebel
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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Bounds for functionally convex optimal control problems
Morgan A Hanson
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Computation of Optimal Controls for a Nuclear Rocket Reactor [PDF]
Harold J. Price, R.R. Mohler
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
A duality theory for abstract mathematical programs with applications to optimal control theory
Richard M. Van Slyke, Roger J.‐B. Wets
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Discussion: “On the Existence of Optimal Controls” (Markus, L., and Lee, E. B., 1962, ASME J. Basic Eng., 84, pp. 13–20) [PDF]
Y. C. Ho
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