A mathematical study for psoriasis transmission with immune-mediated time delays and optimal control strategies. [PDF]
PLoS OneCao X +4 more
europepmc +1 more source
A duality theory for abstract mathematical programs with applications to optimal control theory
, 1968 Richard M. Van Slyke, Roger J.‐B. Wets
openalex +1 more source
Discussion: “On the Existence of Optimal Controls” (Markus, L., and Lee, E. B., 1962, ASME J. Basic Eng., 84, pp. 13–20) [PDF]
, 1962 Y. C. Ho
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
HPV transmission and optimal control of cervical cancer in China. [PDF]
Sci RepRen H, Xu R, Zhang J.
europepmc +1 more source
Closure to “Discussion of ‘Optimal Control Methods for On-Off Sampling Systems’” (1962, ASME J. Basic Eng., 84, pp. 99–100) [PDF]
, 1962 W. L. Nelson
openalex +1 more source
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Molecular Oncology, EarlyView.Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker +3 more
wiley +1 more source
Optimal Feedback Control Minimizing the Effects of Noise Disturbances
, 1966 Suguru Arimoto
openalex +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source