Results 61 to 70 of about 1,651,928 (313)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Event-Triggered Asynchronous Dissipative Control for Markov Jump Systems With Unknown Probabilities
IEEE AccessThis paper investigates the issue of the event-triggered asynchronous dissipative control for Markov jump systems with unknown probabilities and packet losses. A hidden Markov model is used to describe the asynchronous problem.
Huiying Chen +4 more
doaj +1 more source
Robustness Analysis of a Class of Optimal Control Systems [PDF]
Modeling, Identification and Control, 1983 This paper deals with a class of optimal control systems, where the controller. in addition to minimizing a quadratic criterion, also shall give the closed-loop system prescribed eigenvalues.
Ole A. Solheim
doaj +1 more source
, 2004 Frequently, the engineer in charge of a process is faced with optimization problems. In fact, this may cover relatively different ideas, such as parameter identification or process optimization. It is known that the reactive feed flow rate profile for a fed-batch reactor and the temperature or pressure profile to be followed for a batch reactor, will ...
openaire +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A Sufficient Condition for Graphs to Be Super K-Restricted Edge Connected
Discussiones Mathematicae Graph Theory, 2017 For a subset S of edges in a connected graph G, S is a k-restricted edge cut if G − S is disconnected and every component of G − S has at least k vertices.
Wang Shiying, Wang Meiyu, Zhang Lei
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source