Results 61 to 70 of about 22,276,625 (298)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Hamilton-Souplet-Zhang’s Gradient Estimates for Two Types of Nonlinear Parabolic Equations under the Ricci Flow

open access: yesJournal of Function Spaces, 2016
We consider gradient estimates for two types of nonlinear parabolic equations under the Ricci flow: one is the equation ut=Δu+aulog⁡u+bu with a,b being two real constants; the other is ut=Δu+λuα with λ,α being two real constants.
Guangyue Huang, Bingqing Ma
doaj   +1 more source

Global static stability and its relation to gravity waves in the middle atmosphere

open access: yesEarth and Planetary Physics, 2020
The global atmospheric static stability (N2) in the middle atmosphere and its relation to gravity waves (GWs) were investigated by using the temperature profiles measured by the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER ...
Xiao Liu, JiYao Xu, Jia Yue
doaj   +1 more source

Optimal continuous-path control for manipulators with redundant degrees of freedom [PDF]

open access: yesModeling, Identification and Control, 1989
A control system for macro-mini manipulators is presented. A position transformation from the end-effector reference to joint coordinates is found using kinematic optimization.
Olav Egeland, Jan R. Sagli, Bård Jansen
doaj   +1 more source

Optimization Based Robust Control [PDF]

open access: yes, 2013
This entry describes the basic setup of linear robust control and the difficulties typically encountered when designing optimization algorithms to cope with robust stability and performance specifications.
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Event-Triggered Asynchronous Dissipative Control for Markov Jump Systems With Unknown Probabilities

open access: yesIEEE Access
This paper investigates the issue of the event-triggered asynchronous dissipative control for Markov jump systems with unknown probabilities and packet losses. A hidden Markov model is used to describe the asynchronous problem.
Huiying Chen   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Robustness Analysis of a Class of Optimal Control Systems [PDF]

open access: yesModeling, Identification and Control, 1983
This paper deals with a class of optimal control systems, where the controller. in addition to minimizing a quadratic criterion, also shall give the closed-loop system prescribed eigenvalues.
Ole A. Solheim
doaj   +1 more source

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