Results 201 to 210 of about 4,114,836 (337)

915 Optimum Geometry Design of Magnetic Circuit of Thermo-Magnetic Motor : A study on Optimum Shape of Temperature-Sensitive Magnetic Material Pieces Based on Thermal and Magnetic Field Analysis

, 2006
Yoko KIRITA, Mika KOYAMA, Masayuki NAKAMURA   +2 more
openalex   +2 more sources

Optimal Multi-Dimensional Mechanism Design: Reducing Revenue to Welfare Maximization [PDF]

, 2012
Yang Cai, Constantinos Daskalakis, S. Matthew Weinberg   +2 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Mutagenesis-based optimal design of plant peptide phytosulfokine for enhanced biological activity. [PDF]

Comput Struct Biotechnol J
Ye R, Xu C, Ding ZJ, Zheng SJ, Marrink SJ, Zhang D, Zhou R.   +6 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Optimal design of a hybrid ship energy management system under various sea conditions using Model Predictive Control. [PDF]

PLoS One
Mushtaq R, Iqbal M, Khaliq A, Iqbal J.
europepmc   +1 more source

Upon the Optimal Design of a Self-Propelled Double-Cone Mechanism

, 2018
Akio Miyamura, Yoshimasa SUSUKI, Makoto Takahashi, Daiki Matsuo   +3 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

A computational algorithm for optimal design of a bioartificial organ scaffold architecture. [PDF]

PLoS Comput Biol
Bukač M, Čanić S, Muha B, Wang Y.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source