Results 61 to 70 of about 4,071,178 (286)
Nature-Inspired Structures Applied in Heat Transfer Enhancement and Drag Reduction
Micromachines, 2021 Heat exchangers are general equipment for energy exchange in the industrial field. Enhancing the heat transfer of a heat exchanger with low pump energy consumption is beneficial to the maximum utilization of energy.
Zhangyu Zhu +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A-OPTIMAL DESIGN IN NON-LINEAR MODELS TO INCREASE SILICON DIOXIDE PURITY LEVELS
Media StatistikaSilica is the most mineral found on earth and is widely used in industry. Silica used in industry is usually silicon dioxide with a purity ≥ 95% and its often sold at a higher cost.
Ghea Weisha +3 more
doaj +1 more source
Optimized Parameter Design of RC Snubber Circuit forSiC-MOSFET Module
Kongzhi Yu Xinxi Jishu, 2021 This paper proposes a fast optimization design method for RC snubber circuit parameters in order to solve the high switching voltage spikes of SiC while high switching and difficulties in snubber circuit parameters.
SHI Hongliang +6 more
doaj
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Design of Quadratic Optimal Regulator System for State Space Model of Single Phase Inverter Both in Standalone and Gridtie Modes [PDF]
, 2014 Since in 3-phase systems, the reliability of 3-phase Inverter is not good, under such situations Paralleled Inverter Systems are used. Parallel Inverter operation has a major role in uninterruptible power system (UPS) applications. Most of the standalone
Kiran, N. (Nagulapati) +2 more
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