Results 71 to 80 of about 4,384,562 (254)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
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Numerical Study of the Effect of Freestream Turbulence on by-pass Transition in a Boundary Layer [PDF]
, 2014 We use direct numerical simulations in the presence of free-stream turbulence having different values of intensity, T u, and integral length scale, L, in order to determine which kind of structures are involved in the path to transition of a boundary ...
Robinet, Jean Christophe +3 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
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European Journal of Applied Mathematics, 2013 We revisit the American put and call option valuation problems. We derive analytical formulas for the option prices and approximate ordinary differential equations for the optimal exercise boundaries. Numerical simulations yield accurate option prices and comparable computational speeds when benchmarked against the binomial method for calculating ...
openaire +3 more sources
Asymptotically Optimal Multistage Hypothesis Tests [PDF]
, 2004 This thesis investigates variable stage size multistage hypothesis testing in three different contexts, each building on the previous. We first consider the problem of sampling a random process in stages until it crosses a predetermined boundary at ...
Bartroff, Jay L.
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 1998 This document integrates official ground-water data from the United States and Mexico into one data base. These data were exchanged during a series of official meetings held in the offices of the Comisión Internacional de Limites y Aguas and the ...
International Boundary and Water Commission (IBWC)
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Nonlinear optimal perturbations in a Couette flow: bursting and transition [PDF]
, 2013 This paper provides the analysis of bursting and transition to turbulence in a Couette flow, based on the growth of nonlinear optimal disturbances. We use a global variational procedure to identify such optimal disturbances, defined as those initial ...
DE PALMA, Pietro, CHERUBINI, Stefania
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source