Results 131 to 140 of about 2,082,796 (308)

Location of Spanish integrated steel, 1880-1936 [PDF]

open access: yes, 1998
This analysis questions whether or not Biscay was an optimal location for Spanish integrated steel mills at the end of the century and tries to determine Spain's optimal site as coal found substitutes all throughout the twentieth century. The contrast of
Houpt, Stefan
core   +1 more source

Optimizing Support Locations

open access: yes
Abstract Structural topology optimization is usually performed with predetermined support conditions. In this chapter, we present a general method for optimizing support locations and show how it can be integrated with topology optimization.
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Distribution Network Configuration Considering Inventory Cost [PDF]

open access: yes
Inter-city distribution network structure is considered as one of which determine the quantity of economic activities in each city. In the field of operations research, several types of optimal facility location problem and algorithms for them have been ...
Makoto Okumura, Makoto Tsukai
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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