Results 41 to 50 of about 329,852 (266)

On the Optimal Location of Capital

open access: yes, 2000
Abstract In his paper ‘The Optimum Town’, Mirrlees (1972) posed the question, what is the optimal spatial organization of individuals around a town centre in which they work? He characterized the optimal consumption level and residential area to be given to individuals at different distances from the centre and pointed out that, in ...
openaire   +2 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Optimal Location of Discretionary Service Facilities [PDF]

open access: yesTransportation Science, 1992
Automatic teller machines and gasoline service stations are two examples of a growing number of “discretionary service facilities.” In consuming service from these facilities, a significant fraction of customers do so on an otherwise preplanned trip (e.g., on the daily commute to and from work).
Berman, Oded   +2 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Investigation and analysis of wind turbines optimal locations and performance in Iraq [PDF]

open access: yesFME Transactions, 2020
Wind energy is one of the most important types of renewable energy resources in the world. The wind energy is considered friendly to the environment and relatively inexpensive power.
Bashaer Mohammed   +2 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Designing sustainable reverse supply chain network with optimal collection points locations

open access: yesAin Shams Engineering Journal
Reverse supply chain (RSC) optimization is crucial for sustainable operations, as it influences the collection and processing of used products for reuse or disposal.
Mahmoud Elashwah   +3 more
doaj   +1 more source

MODEL FOR LOCATION DEVELOPMENT OF ATM BANKING SERVICE IN URBAN AREA

open access: yesIndonesian Journal of Geography, 2013
The research aims to (iesign a determination modelfor the locations of ICT based economic service particularly the ATM (Automatic Teller Machine) service.
Rini Rachmawati   +3 more
doaj   +1 more source

Quantized Control via Locational Optimization [PDF]

open access: yesIEEE Transactions on Automatic Control, 2006
This paper studies state quantization schemes for feedback stabilization of control systems with limited information. The focus is on designing the least destabilizing quantizer subject to a given information constraint. We explore several ways of measuring the destabilizing effect of a quantizer on the closed-loop system, including (but not limited to)
Francesco Bullo, Daniel Liberzon
openaire   +2 more sources

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