Results 51 to 60 of about 1,666,389 (343)

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Optimized Operation of Integrated Cooling-Electricity-Heat Energy Systems with AA-CAES and Integrated Demand Response

open access: yesEnergies
Integrated energy systems (IESs) have been implemented with the objective of enhancing the efficiency of energy utilization and facilitating the sustainable transition of society and energy systems.
Tiannan Ma   +4 more
doaj   +1 more source

Optimal scheduling and fair servicepolicy for STDMA in underwater networks with acoustic communications [PDF]

open access: yes, 2018
In this work, a multi-hop string network with a single sink node is analyzed. A periodic optimal scheduling for TDMA operation that considers the characteristic long propagation delay of the underwater acoustic channel is presented.
Gini   +7 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A linear programming-based method for job shop scheduling [PDF]

open access: yes, 2012
We present a decomposition heuristic for a large class of job shop scheduling problems. This heuristic utilizes information from the linear programming formulation of the associated optimal timing problem to solve subproblems, can be used for any ...
A. P. J. Vepsalainen   +27 more
core   +4 more sources

Optimal Conversion of Nonlocal Unitary Operations [PDF]

open access: yesPhysical Review Letters, 2002
We study when a non--local unitary operation acting on two $d$--level systems can probabilistically simulate another one when arbitrary local operations and classical communication are allowed. We provide necessary and sufficient conditions for the simulation to be possible.
Dur, W., Vidal, G., Cirac, J. I.
openaire   +5 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Impact of EV charging/discharging strategies on the optimal operation of islanded microgrid

open access: yesThe Journal of Engineering, 2019
This work aims to investigate the impact of electric vehicles (EVs) charging/discharging strategies on the optimal operation of islanded microgrid (MG).
Tanuj Rawat   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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