Results 131 to 140 of about 5,635,969 (342)

Experimental investigation on multi-objective multi-type sensor optimal placement for structural damage detection

Structural Health Monitoring, 2018
An optimal sensor placement with multiple types of sensors could provide informative data of a structure to facilitate its structural damage detection. A response covariance-based multi-objective multi-type sensor optimal placement method has been thus ...
Jianfu Lin, You‐lin Xu, S. Zhan
semanticscholar   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Robust Simultaneous Distribution Network Reconfiguration and Optimal Placement of Renewable Distributed Generations Based on the Information Gap Decision Theory

Engineering Reports
Integration of distributed generation (DG) units in distribution networks (DNs) has some benefits, such as improvement in voltage profile, decrease in power losses, and reduction in operation costs.
Mohsen Rostami, Abouzar Samimi, Hossein Shateri, Mohammad Farahani   +3 more
doaj   +1 more source

STARMAP: Spaceborne Target Acquisition Radar With Meta-RL Assisted Placement

IEEE Open Journal of the Communications Society
The urgent requirement to monitor and identify unmanned aerial systems (UASs) within restricted airspace has become increasingly critical. Traditional methods fail to detect low-observable (LO) UASs effectively, thus presenting considerable threats in ...
Alireza Famili, Shihua Sun, Tolga Atalay, Angelos Stavrou   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Optimal placement of flexible ureteral access sheath in retrograde intrarenal surgery. [PDF]

Urolithiasis, 2023
Chen Y, Cheng X, Yang H, Deng W, Chen L, Wang G, Zhou X.   +6 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Three-Layer Framework Integrating Optimal Placement of Supervisory, Control, and Acquisition System Measurements with Clustering-Based Electric Substations Selection for State Estimation of Medium-Voltage Distribution Networks

Applied Sciences
One of the biggest challenges, both from a technical and economic point of view, of the Distribution Network Operators refers to identifying the locations (electric distribution substations) integrated into a supervisory, control, and acquisition (SCADA)
Vasilica Dandea, Stefania Galbau, Mihai-Alexandru Baciu, Gheorghe Grigoras   +3 more
doaj   +1 more source