Results 111 to 120 of about 2,827,333 (249)
Comparative Study of Profiled School Scheduling Programs in Lithuania
Informatics in Education, 2005 Solution of the problem of optimal school scheduling is very important to make the work of comprehensive schools more effective. Here the sequence of teaching subjects, regarded as tools, can be changed. One needs to reduce the sum of gaps (“empty” hours)
Rita GAIDUKEVICIENE, Eugenijus KURILOVAS
doaj +1 more source
Marginal productivity index policies for scheduling a multiclass delay-/loss-sensitive queue [PDF]
, 2005 We address the problem of scheduling a multiclass M/M/1 queue with a finite dedicated buffer for each class. Some classes are delay-sensitive, modeling real-time traffic (e.g.
Niño-Mora, José +2 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Modeling and solving the periodic maintenance problem. [PDF]
We study the problem of scheduling maintenance services. Given is a set of m machines and integral cost-coefficients a(i) and b(i) for each machine i (1Branch-and-price; Column generation; Costs; Linear programming; Model; Models; Optimal; Scheduling ...
Grigoriev, A +2 more
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Solution and quality robust project scheduling: a methodological framework. [PDF]
The vast majority of the research efforts in project scheduling over the past several years has concentrated on the development of exact and suboptimal procedures for the generation of a baseline schedule assuming complete information and a deterministic
Herroelen, Willy, Leus, Roel
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Optimal scheduling of smart home appliances using mixed-integer linear programming [PDF]
, 2012 In the last years we have witnessed an increasing interest in smart buildings, in particular for what concerns optimal energy management, renewable energy sources, and smart appliances.
Sartor, Giorgio
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source