Results 81 to 90 of about 51,892 (262)

Source-network-load-storage collaborated two-stage power dispatch of active distribution network with conditional value-at-risk

open access: yesInternational Journal of Electrical Power & Energy Systems
The high penetration of distributed wind turbines (WT) and photovoltaics (PV) brings temporal volatility and uncertainty to their output, posing significant challenges to the optimal scheduling of distribution networks.
Shiwei Xia   +7 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Comparative Study of Profiled School Scheduling Programs in Lithuania

open access: yesInformatics in Education, 2005
Solution of the problem of optimal school scheduling is very important to make the work of comprehensive schools more effective. Here the sequence of teaching subjects, regarded as tools, can be changed. One needs to reduce the sum of gaps (“empty” hours)
Rita GAIDUKEVICIENE, Eugenijus KURILOVAS
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Adaptive genetic algorithm for computer course scheduling system under the background of educational informatization

open access: yesSystems and Soft Computing
Currently, traditional scheduling methods are difficult to cope with the increasing demand and complexity of education, especially when dealing with large-scale data, diverse course schedules, and personalized teaching needs.
Lingzhi Yan, Hua Deng
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Optimal scheduling of the stand‐alone micro grids considering the reliability cost

open access: yesThe Journal of Engineering
In order to prevent wastage of generated power of renewable resources, the energy storage systems can be utilized in the stand‐alone micro grids to store the excess produced power of the renewable generation units.
Ayoub Nargeszar   +3 more
doaj   +1 more source

Risk-Averse Optimal Scheduling of Regional Electricity-Heating Integrated Energy System Considering Interface with Microgrids

open access: yesCSEE Journal of Power and Energy Systems
A regional electricity-heating integrated energy system (REH-IES) can make extensive use of renewable energy sources, realize complementary and coordinated operation of multiple energy sources, reduce carbon emissions and promote the development of zero ...
Houhe Chen   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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