Results 91 to 100 of about 86,360 (312)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

On electrical load tracking scheduling for a steel plant [PDF]

, 2010
Nolde and Morari (2010) study a steel manufacturing scheduling problem where the tasks must be scheduled such that electricity consumption matches to a pre-specified periodic energy chart.
Artigues, Christian, Christian Artigues, Haït, Alain, Alain Haït   +3 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Optimization Pine Plantation Forest Management in Kediri FMU Regional Division II East Java

Jurnal Manajemen Hutan Tropika, 2017
Pine forest management today has not already reached its optimal state. The abnormal pine stand structure will cause a decrease in the production of pine resin.
Andrie Ridzki Prasetyo, Muhamad Buce Saleh, Sudarsono Soedomo   +2 more
doaj   +3 more sources

RESCON: Educational project scheduling software. [PDF]

In this article we discuss a freely downloadable educational software tool for illustrating project scheduling and project management concepts. The tool features exact and heuristic scheduling procedures and visualizes project networks, project schedules,
Deblaere, Filip, Herroelen, Willy, Demeulemeester, Erik   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Source-network-load-storage collaborated two-stage power dispatch of active distribution network with conditional value-at-risk

International Journal of Electrical Power & Energy Systems
The high penetration of distributed wind turbines (WT) and photovoltaics (PV) brings temporal volatility and uncertainty to their output, posing significant challenges to the optimal scheduling of distribution networks.
Shiwei Xia, Yifeng Wang, Xinyuan Hu, Yuting Yan, Mingze Tong, Haowen Liang, Xiaoyun Wu, Jian Huo   +7 more
doaj   +1 more source

Comparative Study of Profiled School Scheduling Programs in Lithuania

Informatics in Education, 2005
Solution of the problem of optimal school scheduling is very important to make the work of comprehensive schools more effective. Here the sequence of teaching subjects, regarded as tools, can be changed. One needs to reduce the sum of gaps (“empty” hours)
Rita GAIDUKEVICIENE, Eugenijus KURILOVAS
doaj   +1 more source

Power systems generation scheduling and optimisation using evolutionary computation techniques

, 1996
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Optimal generation scheduling attempts to minimise the cost of power production while satisfying the various operation constraints and physical limitations ...
Orero, S.O, Orero, Shadrack Otieno
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source