Results 101 to 110 of about 2,749,222 (295)

Optimization Models for Scheduling of Jobs

Journal of Research of the National Institute of Standards and Technology, 2006
This work is motivated by a particular scheduling problem that is faced by logistics centers that perform aircraft maintenance and modification. Here we concentrate on a single facility (hangar) which is equipped with several work stations (bays). Specifically, a number of jobs have already been scheduled for processing at the facility; the starting ...
Indika, S. H. Sathish, Shier, Douglas R.
openaire   +2 more sources

Adaptive genetic algorithm for computer course scheduling system under the background of educational informatization

Systems and Soft Computing
Currently, traditional scheduling methods are difficult to cope with the increasing demand and complexity of education, especially when dealing with large-scale data, diverse course schedules, and personalized teaching needs.
Lingzhi Yan, Hua Deng
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Risk-Averse Optimal Scheduling of Regional Electricity-Heating Integrated Energy System Considering Interface with Microgrids

CSEE Journal of Power and Energy Systems
A regional electricity-heating integrated energy system (REH-IES) can make extensive use of renewable energy sources, realize complementary and coordinated operation of multiple energy sources, reduce carbon emissions and promote the development of zero ...
Houhe Chen, Di Wang, Chuqiao Lin, Rufeng Zhang, Tao Jiang, Xue Li   +5 more
doaj   +1 more source

Comparative Study of Profiled School Scheduling Programs in Lithuania

Informatics in Education, 2005
Solution of the problem of optimal school scheduling is very important to make the work of comprehensive schools more effective. Here the sequence of teaching subjects, regarded as tools, can be changed. One needs to reduce the sum of gaps (“empty” hours)
Rita GAIDUKEVICIENE, Eugenijus KURILOVAS
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

RESCON: Educational project scheduling software. [PDF]

In this article we discuss a freely downloadable educational software tool for illustrating project scheduling and project management concepts. The tool features exact and heuristic scheduling procedures and visualizes project networks, project schedules,
Deblaere, Filip, Herroelen, Willy, Demeulemeester, Erik   +2 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Restless bandit marginal productivity indices II: multiproject case and scheduling a multiclass make-to-order/-stock M/G/1 queue [PDF]

, 2004
This paper develops a framework based on convex optimization and economic ideas to formulate and solve approximately a rich class of dynamic and stochastic resource allocation problems, fitting in a generic discrete-state multi-project restless bandit ...
Niño-Mora, José, Niño Mora, José
core   +1 more source