Results 121 to 130 of about 86,360 (312)

Optimal scheduling of smart home appliances using mixed-integer linear programming [PDF]

open access: yes, 2012
In the last years we have witnessed an increasing interest in smart buildings, in particular for what concerns optimal energy management, renewable energy sources, and smart appliances.
Sartor, Giorgio
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Integrating nurse and surgery scheduling. [PDF]

open access: yes
Scheduling; Surgery scheduling; International; Theory; Applications; Euro; Researchers;
Belien, Jeroen, Demeulemeester, Erik
core  

Marginal productivity index policies for scheduling a multiclass delay-/loss-sensitive queue [PDF]

open access: yes, 2005
We address the problem of scheduling a multiclass M/M/1 queue with a finite dedicated buffer for each class. Some classes are delay-sensitive, modeling real-time traffic (e.g.
Niño-Mora, José   +2 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Solving two production scheduling problems with sequence-dependent set-up times [PDF]

open access: yes
In today s competitive markets, the importance of good scheduling strategies in manufacturing companies lead to the need of developing efficient methods to solve complex scheduling problems.
Helena Ramalhinho-Lourenço   +1 more
core  

Scheduling aircraft landings - the static case

open access: yes, 2000
This is the publisher version of the article, obtained from the link below.In this paper, we consider the problem of scheduling aircraft (plane) landings at an airport.
Abramson, D.   +7 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

An optimal-control based integrated model of supply chain

open access: yes
Problems of supply chain scheduling are challenged by high complexity, combination of continuous and discrete processes, integrated production and transportation operations as well as dynamics and resulting requirements for adaptability and stability ...
Ivanov, Dmitry
core   +1 more source

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