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Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

On Optimal Scheduling

American Economic Journal: Microeconomics
We consider a decision-maker sequentially choosing among alternatives when periodic payoffs depend on both chosen and unchosen alternatives in that period. We show that when flow payoffs are the sum or product of payoffs from chosen and unchosen alternatives, the optimal policy is an index policy. We characterize key properties of the optimal dynamics
Kfir Eliaz   +2 more
openaire   +2 more sources

Tri-objective optimal scheduling of smart energy hub system with schedulable loads

Journal of Cleaner Production, 2019
Many researches have investigated the optimal energy scheduling to meet the demand regarding the sustainable development issues and the economic and environmental indices. The energy hub system (EHS) is introduced as an appropriate framework in which the
Heydar Chamandoust   +2 more
exaly   +2 more sources

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