Results 91 to 100 of about 2,756,714 (295)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
An optimal procedure for the unconstrained max-NPV project scheduling problem with generalized precedence relations. [PDF]
The unconstrained max-npv project scheduling problem involves the scheduling of the activities of a project in order to maximize its net present value. Assume a project represented in activity-on-mode (AoN) notation, in which the activities have a known ...
De Reyck, B, Herroelen, Willy
core
Optimal scheduling of the stand‐alone micro grids considering the reliability cost
In order to prevent wastage of generated power of renewable resources, the energy storage systems can be utilized in the stand‐alone micro grids to store the excess produced power of the renewable generation units.
Ayoub Nargeszar +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
An optimal-control based integrated model of supply chain [PDF]
Problems of supply chain scheduling are challenged by high complexity, combination of continuous and discrete processes, integrated production and transportation operations as well as dynamics and resulting requirements for adaptability and stability ...
Ivanov, Dmitry
core
Lot streaming and batch scheduling: splitting and grouping jobs to improve production efficiency
This thesis deals with issues arising in manufacturing, in particular related to production efficiency. Lot streaming refers to the process of splitting jobs to move production through several stages as quickly as possible, whereas batch scheduling ...
Possani, Edgar
core +1 more source
The high penetration of distributed wind turbines (WT) and photovoltaics (PV) brings temporal volatility and uncertainty to their output, posing significant challenges to the optimal scheduling of distribution networks.
Shiwei Xia +7 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Fifty years of scheduling: a survey of milestones [PDF]
Scheduling has become a major field within operational research with several hundred publications appearing each year. This paper explores the historical development of the subject since the mid 1950s when the landmark publications started to appear.
Strusevich, Vitaly A. +5 more
core +1 more source
Currently, traditional scheduling methods are difficult to cope with the increasing demand and complexity of education, especially when dealing with large-scale data, diverse course schedules, and personalized teaching needs.
Lingzhi Yan, Hua Deng
doaj +1 more source

