Results 51 to 60 of about 52,420 (263)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An Optimization Scheduler in the Intranet Grid
, 2016 Scheduling of processes is the basic task for a grid computing. This role is responsible for the allocation of time for computational agents. The calculation agent can include a wide range of devices, based on various types of computer systems. Is it possible to efficiently build a grid infrastructure in the company environment. The grid can be used in
Petr Lukasik, Martin Sysel
openaire +2 more sources
Optimal outpatient appointment scheduling [PDF]
Health Care Management Science, 2007 In this paper optimal outpatient appointment scheduling is studied. A local search procedure is derived that converges to the optimal schedule with a weighted average of expected waiting times of patients, idle time of the doctor and tardiness (lateness) as objective. No-shows are allowed to happen. For certain combinations of parameters the well-known
Kaandorp, G., Koole, G.M.
openaire +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Scheduling and control of high throughput screening systems with uncertainties and disturbances
Production and Manufacturing Research: An Open Access Journal, 2022 Based on the existing research work on the modeling and control of cyclically operated high-throughput screening systems, this paper presents the scheduling and control of high-throughput screening systems with uncertainties and disturbances.
Adetola Oke +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Scheduling Optimization of Linear Schedule with Constraint Programming
Computer-Aided Civil and Infrastructure Engineering, 2018 In recent decades, construction project scheduling optimization has received extensive attention from the research community. However, the most commonly used scheduling approach, the critical path method, is often inapplicable to transportation-type linear projects.
Yuanjie Tang +4 more
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Properties of optimal schedules in preemptive shop scheduling
Discrete Applied Mathematics, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Philippe Baptiste +5 more
openaire +4 more sources