Results 91 to 100 of about 2,749,222 (295)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

An optimal procedure for the unconstrained max-NPV project scheduling problem with generalized precedence relations. [PDF]

open access: yes
The unconstrained max-npv project scheduling problem involves the scheduling of the activities of a project in order to maximize its net present value. Assume a project represented in activity-on-mode (AoN) notation, in which the activities have a known ...
De Reyck, B, Herroelen, Willy
core  

Optimal scheduling of the stand‐alone micro grids considering the reliability cost

open access: yesThe Journal of Engineering
In order to prevent wastage of generated power of renewable resources, the energy storage systems can be utilized in the stand‐alone micro grids to store the excess produced power of the renewable generation units.
Ayoub Nargeszar   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

An optimal-control based integrated model of supply chain [PDF]

open access: yes
Problems of supply chain scheduling are challenged by high complexity, combination of continuous and discrete processes, integrated production and transportation operations as well as dynamics and resulting requirements for adaptability and stability ...
Ivanov, Dmitry
core  

Lot streaming and batch scheduling: splitting and grouping jobs to improve production efficiency

open access: yes, 2001
This thesis deals with issues arising in manufacturing, in particular related to production efficiency. Lot streaming refers to the process of splitting jobs to move production through several stages as quickly as possible, whereas batch scheduling ...
Possani, Edgar
core   +1 more source

Source-network-load-storage collaborated two-stage power dispatch of active distribution network with conditional value-at-risk

open access: yesInternational Journal of Electrical Power & Energy Systems
The high penetration of distributed wind turbines (WT) and photovoltaics (PV) brings temporal volatility and uncertainty to their output, posing significant challenges to the optimal scheduling of distribution networks.
Shiwei Xia   +7 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Fifty years of scheduling: a survey of milestones [PDF]

open access: yes, 2009
Scheduling has become a major field within operational research with several hundred publications appearing each year. This paper explores the historical development of the subject since the mid 1950s when the landmark publications started to appear.
Strusevich, Vitaly A.   +5 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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