Results 71 to 80 of about 86,360 (312)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Application of hyperbolic partial differential equations in global optimal scheduling of UAV

open access: yesAlexandria Engineering Journal, 2020
The global optimal scheduling of UAV (unmanned aerial vehicle) navigation channel is studied. Firstly, a multi-channel optimal scheduling mathematical model based on the HPDEs (hyperbolic partial differential equations) wave combination optimization is ...
Chong Tian, Kuo-Chi Chang, JinSong Chen
doaj   +1 more source

A linear programming-based method for job shop scheduling [PDF]

open access: yes, 2012
We present a decomposition heuristic for a large class of job shop scheduling problems. This heuristic utilizes information from the linear programming formulation of the associated optimal timing problem to solve subproblems, can be used for any ...
Bülbül, Kerem, Kaminsky, Philip
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Optimal Sizing of Energy Storage in Photovoltaic-Energy Storage DC Distribution Network Considering Uncertainty

open access: yes南方能源建设
[Objective] In order to balance the relationship between multiple objectives in the photovoltaic-energy storage DC distribution network and realize the optimal scheduling of energy storage capacity, an optimal scheduling method for energy storage ...
Junyang XIAO   +4 more
doaj   +1 more source

Project scheduling under uncertainty using fuzzy modelling and solving techniques [PDF]

open access: yes, 2013
In the real world, projects are subject to numerous uncertainties at different levels of planning. Fuzzy project scheduling is one of the approaches that deal with uncertainties in project scheduling problem.
Masmoudi, Malek, Haït, Alain
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Resource-constrained project scheduling. [PDF]

open access: yes
: Resource-constrained project scheduling involves the scheduling of project activities subject to precedence and resource constraints in order to meet the objective(s) in the best possible way. The area covers a wide variety of problem types.
Herroelen, Willy, Demeulemeester, Erik
core  

Control design and gain-scheduling using observer-based structures [PDF]

open access: yes, 2012
we present the procedure to compute the observer-based realization of a given controller and a given model. The application of this procedure to a very simple missile model is proposed in the third section to illustrate the interest of observer-based ...
Daniel Alazard, Alazard, Daniel
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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