Results 41 to 50 of about 3,761,593 (295)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Optimal Sensors Placement to Enhance Damage Detection in Composite Plates [PDF]

open access: yes, 2014
This paper examines an important challenge in ultrasonic structural health monitoring (SHM), which is the problem of the optimal placement of sensors in order to accurately detect and localize damages.
MOREL, Julien   +5 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Optimizing the Sensor Placement for Foot Plantar Center of Pressure without Prior Knowledge Using Deep Reinforcement Learning

open access: yesSensors, 2020
We study the foot plantar sensor placement by a deep reinforcement learning algorithm without using any prior knowledge of the foot anatomical area. To apply a reinforcement learning algorithm, we propose a sensor placement environment and reward system ...
Cheng-Wu Lin   +4 more
doaj   +1 more source

Sensor Placement in an Irregular 3D Surface for Improving Localization Accuracy Using a Multi-Objective Memetic Algorithm

open access: yesSensors, 2023
Accurate localization is a critical task in underwater navigation. Typical localization methods use a set of acoustic sensors and beacons to estimate relative position, whose geometric configuration has a significant impact on the localization accuracy ...
Paula A. Graça   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Optimal Sensor Placement Problems Under Uncertainty: Models and Applications

open access: yes, 2019
The problem of optimally placing sensors can often be formulated as a facility location problem. In the literature of operations research, facility location problems are mathematical optimization problems where one or more facilities must be placed in ...
Todd Zhen (7407275)
core   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Pressure Sensor Placement for Leak Localization in Water Distribution Networks Using Information Theory

open access: yesSensors, 2022
This paper presents a method for optimal pressure sensor placement in water distribution networks using information theory. The criterion for selecting the network nodes where to place the pressure sensors was that they provide the most useful ...
Ildeberto Santos-Ruiz   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy