Results 91 to 100 of about 3,140,982 (289)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Application of Reinforcement Learning to Solve Rubrik’s Cube with Markov Decision Process

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)
The Rubik's Cube is a complex puzzle with an enormous number of possible configurations, making it a challenging problem for both humans and computational methods to solve.
Defni, Andi Fathul Mukminin, Ainil Mardhiah, Titin Ritmi, Junaldi, Yuhefizar, Fibriyanti   +6 more
doaj   +1 more source

МОДЕЛИРОВАНИЕ ВЫБОРА РУКОВОДСТВОМ ВЫСШЕГО УЧЕБНОГО ЗАВЕДЕНИЯ ОПТИМАЛЬНОГО РЕШЕНИЯ, СОГЛАСОВАННОГО С УПРАВЛЯЮЩИМИ РЕШЕНИЯМИ ЕГО ФИЛИАЛОВ

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2013
В работе рассмотрена модель выбора руководством высшего учебного заведения оптимального решения о распределении наборов абитуриентов в своих филиалах.
Паровик, Р.И., Parovik, R.I.
doaj   +1 more source

Optimal Actuator Location of the Minimum Norm Controls for Stochastic Heat Equations

, 2017
In this paper, we study the approximate controllability for the stochastic heat equation over measurable sets, and the optimal actuator location of the minimum norm controls.
Yang, Donghui, Zhong, Jie
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Engineering Islets From Stem Cells: The Optimal Solution for the Treatment of Diabetes? [PDF]

Front Immunol, 2022
Du S, Li Y, Geng Z, Zhang Q, Buhler LH, Gonelle-Gispert C, Wang Y.   +6 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Fast Adaptation of Manipulator Trajectories to Task Perturbation by Differentiating through the Optimal Solution. [PDF]

Sensors (Basel), 2022
Srikanth S, Babu M, Masnavi H, Kumar Singh A, Kruusamäe K, Krishna KM.   +5 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Optimal solution of the fractional order breast cancer competition model. [PDF]

Sci Rep, 2021
Hassani H, Machado JAT, Avazzadeh Z, Safari E, Mehrabi S.   +4 more
europepmc   +1 more source