Results 171 to 180 of about 522,389 (335)

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Stochastic analysis of Mpox epidemiology with vaccination strategies and environmental persistence. [PDF]

Sci Rep
Khondaker F, Kamrujjaman M.
europepmc   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

Decision, Inference, and Information: Formal Equivalences Under Active Inference. [PDF]

Entropy (Basel)
Sweeney P, Ruiz-Serra J, Harré MS.
europepmc   +1 more source

STOCHASTIC OPTIMAL CONTROL ANALYSIS FOR THE COVID-19 EPIDEMIC MODEL UNDER REAL STATISTICS

, 2022
Peijiang Liu, Abdullahi Yusuf, Ting Cui, Anwarud Din   +3 more
openalex   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Deciphering cell-fate trajectories using spatiotemporal single-cell transcriptomic data. [PDF]

NPJ Syst Biol Appl
Zhang Z, Wang Z, Sun Y, Shen J, Peng Q, Li T, Zhou P.   +6 more
europepmc   +1 more source

Strong Proton‐Phonon Coupling Drives Fast Ion Transport in Perovskites

Advanced Science, EarlyView.
Experimental and computational phonon analysis of ABO3‐type proton conductor BaSnO3 shows that substitution on the B‐site with yttrium forms an imaginary phonon mode which is instrumental for the function as proton conductor. This overcompensates the adverse proton trapping effect of the yttrium.
Alexey Rulev, Nobumoto Nagasawa, Hongxin Wang, Vladimir Pomjakushin, Martin Kunz, Yoshitaka Yoda, Stephen P. Cramer, Qianli Chen, Artur Braun   +8 more
wiley   +1 more source

Minimal time robust control for two superconducting qubits. [PDF]

Sci Rep
George N, Allen JL, Kosut R, Ginossar E.
europepmc   +1 more source

OPTIMAL STOCHASTIC CONTROL PRINCIPLE AND ITS’ APPLICATIONIN FACTORY CONSUMPTION MODEL [PDF]

, 2019
N. K. Oladejo, O. Adebimpe, Abimbola Abolarinwa, S.O. Salawu, Adewale F. Lukman   +4 more
openalex