Results 241 to 250 of about 1,450,399 (320)

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

A machine learning model to simplify recognition of patients with atrial fibrillation based on diagnostic codes in Swedish primary health care. [PDF]

BMC Med Inform Decis Mak
Norrman A, Wachtler C, Wändell P, Eriksson J, Ruge T, Brynedal B, Hasselström J, Kahan T, Carlsson AC.   +8 more
europepmc   +1 more source

Design principles of the cytotoxic CD8⁺ T cell response. [PDF]

Proc Natl Acad Sci U S A
Ukogu OA, Montague Z, Altan-Bonnet G, Nourmohammad A.   +3 more
europepmc   +1 more source

Experimentally achieving minimal dissipation via thermodynamically optimal transport. [PDF]

Nat Commun
Oikawa S, Nakayama Y, Ito S, Sagawa T, Toyabe S.   +4 more
europepmc   +1 more source

Enhanced twin delayed DDPG with prioritized experience replay and Noisy Nets for regional economic dispatch. [PDF]

Sci Rep
Xu C, Hayashi N, Inuiguchi M, Raymond WJK, Mokhlis H, Illias HA.   +5 more
europepmc   +1 more source

Lineage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors. [PDF]

Elife
Salvidge W, Brimson C, Gruenheit N, Huang LY, Pears C, Wolf J, Thompson C.   +6 more
europepmc   +1 more source

Assessing the effects of limited vaccine supply on risk-based vaccination strategies in regions of endemic foot-and-mouth disease

Guyver-Fletcher G, Tildesley M.
europepmc   +1 more source

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Optimal stochastic control

Automatica, 1969
It is indicated that optimal stochastic control is still in its infancy, and that at the present time it has little use in practice although a wide class of problems can be precisely stated. A brief survey of the problem involved in attempting to formulate and to solve optimal stochastic control problems is discussed along with the corresponding ...
W. Wonham
semanticscholar   +2 more sources

On optimal stochastic control with smoothed information

Information Sciences, 1968
Abstract This paper presents a generalization of the Separation Theorem of stochastic control. The generalization consists in assuming observations ahead of running time. We consider the following problem of optimal pursuit: Given noisy incomplete observations of a linear stochastic system, control another linear stochastic system so that a quadratic
A. Lindquist
semanticscholar   +3 more sources