Results 181 to 190 of about 7,890,396 (298)

Ambiguities in Selecting the Optimal Strategy for the Nonculprit Stenosis in STEMI

JACC: Cardiovascular Interventions, 2017
Lloyd W, Klein, Amir, Lotfi
openaire   +2 more sources

Calcified Thoracic Disc Herniation: Surgical Management, Surgical Approaches, and Decision-Making. [PDF]

Orthop Rev (Pavia)
Kapetanakis S, Chatzivasiliadis M, Cappin B, Tsioulas P, Poultsides L, Konstantinou P, Siopis C, Pinto I, Ditsios K.   +8 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Totality of the Evidence: Optimizing Dosage Selection Strategies in Oncology

Journal of Clinical Oncology
Laura A. Levit, Mirat Shah, Mark J. Ratain, Elizabeth Garrett-Mayer, Atiqur Rahman, Marc Theoret, R. Donald Harvey   +6 more
openaire   +3 more sources

Editorial: Chimeric antigen receptor T cell therapies and bispecific antibodies in hematologic malignancies. [PDF]

Front Oncol
Zhu Y.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Optimal dose of intra-operative dexmedetomidine for postoperative delirium prevention. [PDF]

Anaesthesia
Guo YN, Liu HC.
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

An application of weighted support vector machines to individualized second-line therapy selection after levodopa in Parkinson's disease. [PDF]

Front Hum Neurosci
Pham CT, Schneider RB, Venuto CS, Smith G, Brehm ZP, McDermott MP, Ertefaie A.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source