Results 71 to 80 of about 7,890,396 (298)
Journal of Theoretical and Applied Electronic Commerce ResearchThe rapid advancement of digital technology has blurred the line between online and brick-and-mortar stores, leading to the proliferation of omnichannel retailing.
Jing Yu, Yufei Ren, Chi Zhou
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Intelligent and Converged NetworksWith the increasing demand for ocean communication, trans-air-sea wireless optical communication (WOC) has attracted growing attention. Due to spatial variations in signal attenuation, low-power regions are more susceptible to signal loss and channel ...
Jiehong Wu, Wenna Zhang, Cunqian Yu
doaj +1 more source
Dynamic Portfolio Strategy Using Clustering Approach.
PLoS ONE, 2017 The problem of portfolio optimization is one of the most important issues in asset management. We here propose a new dynamic portfolio strategy based on the time-varying structures of MST networks in Chinese stock markets, where the market condition is ...
Fei Ren +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Optimal portfolio selection for cash-flows with bounded capital at risk. [PDF]
Optimal; Optimal portfolio selection; Portfolio; Selection; Cash flow; Capital at risk; Risk;
Goovaerts, Marc +3 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission
, 2014 Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/1/14Official website of the Connecticut Judicial Selection Commission ...
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