Results 21 to 30 of about 18,096,857 (248)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Setting Priorities for Innovation Policy and Evaluating Their Performance: Evidence from Europe and Lessons for Ukraine

open access: yesForesight and STI Governance, 2012
Setting priorities for supporting prospective technologies and activities is a key issue for science, technology and innovation (STI) policy. The general principles of priority-setting practices vary significantly across countries in terms of process ...
Gudrun Rumpf
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Optimal digitalization and pricing decisions in a dual-channel agri-food supply chain under subsidy mechanisms: a decision analytic framework

open access: yesFrontiers in Sustainable Food Systems
IntroductionDigital traceability is essential to ensure the transparency of the agricultural supply chain. However, manufacturers face a key strategic dilemma: the high initial investment cost hinders the investment in traceability, and multi-channel ...
Haiyan Zhong, Yin Xiao, Hong Huo
doaj   +1 more source

Regional competitiveness in the context of “New industrial policy” – the case of Croatia [PDF]

open access: yesZbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2017
The purpose of this paper is to do research on regional conditions that are most conducive to maximising the positive effects of the implementation of “New industrial policy” (policy based on Smart specialisation strategy) to regional competitiveness ...
Katarina Bačić, Zoran Aralica
doaj   +1 more source

Ways to Innovate the System to Deliver Innovative Outcomes of Science and Technology to Society

open access: yes, 2022
1. Background and Purpose The achievements made in the process of technology innovation have various purposes but their ultimate goal is the same. They aim to be applied somewhere across the society where we live.
Cha, J.   +1 more
core   +3 more sources

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Interdisciplinary challenges in bio-energy carbon capture utilization & storage deployment: A review

open access: yesCarbon Capture Science & Technology
Bioenergy with Carbon Capture, Utilization, and Storage (BECCUS) is an innovative technology that has the potential to contribute significantly to global climate change mitigation efforts by simultaneously removing atmospheric carbon dioxide through the ...
Fan David Yeung   +4 more
doaj   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad   +22 more
wiley   +1 more source

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