Results 111 to 120 of about 667,528 (289)

Optimal Transport for Diffeomorphic Registration [PDF]

, 2017
This paper introduces the use of unbalanced optimal transport methods as a similarity measure for diffeomorphic matching of imaging data. The similarity measure is a key object in diffeomorphic registration methods that, together with the regularization on the deformation, defines the optimal deformation. Most often, these similarity measures are local
Feydy, Jean, Charlier, Benjamin, Vialard, François-Xavier, Peyré, Gabriel   +3 more
openaire   +4 more sources

Joint Distribution Optimal Transportation for Domain Adaptation

, 2017
This paper deals with the unsupervised domain adaptation problem, where one wants to estimate a prediction function $f$ in a given target domain without any labeled sample by exploiting the knowledge available from a source domain where labels are known.
Courty, Nicolas, Flamary, Rémi, Habrard, Amaury, Rakotomamonjy, Alain   +3 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Quadratic-form optimal transport

Mathematical Programming
We introduce the framework of quadratic-form optimal transport (QOT), whose transport cost has the form $\iint c\,\mathrm{d}π\otimes\mathrm{d}π$ for some coupling $π$ between two marginals. Interesting examples of quadratic-form transport cost and their optimization include inequality measurement, the variance of a bivariate function, covariance ...
Ruodu Wang, Zhenyuan Zhang
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

OPTIMAL FEASIBLE SOLUTIONS TO A ROAD FREIGHT TRANSPORTATION PROBLEM

Malaysian Journal of Computing, 2020
For twenty decades, there is a visible ever forward advancement in the technology of mobility, vehicles and transportation system in general. However, there is no "cure-all" remedy ideal enough to solve all life problems but mathematics has proven that ...
Tolulope Latunde, Joseph Oluwaseun Richard, Opeyemi Odunayo Esan, Damilola Deborah Dare
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Climate Optimized Air Transport

, 2012
Aviation climate impact is caused by CO2 and non-CO2 emissions where the climate effect of non-CO2 emissions depends on weather and aircraft route. An aviation system with minimum climate impact differs from a system with minimum emissions. Considerable potential exists to reduce the climate impact of aviation by weather- and cost-dependent climate ...
Matthes, Sigrun, Schumann, Ulrich, Grewe, Volker, Frömming , Christine, Dahlmann, Katrin, Koch , Alexander, Mannstein , Hermann   +6 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Modeling the Optimal Transportation for Acute Stroke Treatment : Impact of Diurnal Variations in Traffic Rate. [PDF]

Clin Neuroradiol, 2021
Ernst M, Psychogios MN, Schlemm E, Holodinsky JK, Kamal N, Rodt T, Henningsen H, Kraemer C, Thomalla G, Fiehler J, Brekenfeld C.   +10 more
europepmc   +1 more source