Results 61 to 70 of about 343,466 (294)

Optimistic concurrency control revisited [PDF]

, 1994
Several years ago optimistic concurrency control gained much attention in the database community. However, two-phase locking was already well established, especially in the relational database market. Concerning traditional database systems most developers felt that pessimistic concurrency control might not be the best solution for concurrency control,
openaire   +3 more sources

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

Advanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier, Keerthi Thirtamara Rajamani, Shai Netser, Shlomo Wagner, Hala Harony‐Nicolas   +4 more
wiley   +1 more source

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

PLXDC1+ Tumor‐Associated Pancreatic Stellate Cells Promote Desmoplastic and Immunosuppressive Niche in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du, Yizhou Zhao, Judong Li, Jiaxin Wang, Shenglan You, Yao Zhang, Li Zhang, Jihong Yang, Hamid Alinejad‐Rokny, Shujie Cheng, Chenghao Shao, Duowu Zou, Youqiong Ye   +12 more
wiley   +1 more source

Trifunctional Sialylation‐Based SF‐ZIF@NA Hydrogel for Selective Osteoclast Inhibition and Enhanced Bone‐Vessel Regeneration in Osteoporotic Bone Defects

Advanced Science, EarlyView.
This study introduces the SF‐ZIF@NA hydrogel system for osteoporotic bone defect treatment. The hydrogel inhibits osteoclast fusion by removing sialic acid and preserves the anabolic function of precursor osteoclasts (pOCs). It also releases Zn2⁺ in acidic conditions, promoting osteogenesis and angiogenesis.
Zhengrong Chen, Wenxin Yang, Yong Tang, Qianqian Dong, Kui Huang, Jiulin Tan, Jie Zhang, Juan Cai, Qixiu Yu, Qijie Dai, Jianzhong Xu, Shuquan Guo, Ce Dou, Fei Luo   +13 more
wiley   +1 more source

Reciprocal relationships between personality disorders and eating disorders in a prospective 17‐year follow‐up study

International Journal of Eating Disorders, Volume 55, Issue 12, Page 1753-1764, December 2022., 2022
Abstract Objective This study aimed to report the presence of categorical and dimensional personality disorders (PD) in adults with longstanding eating disorders (ED) over a period of 17 years and to investigate whether changes in PD predict changes in ED symptoms or vice versa.
Hanna Punsvik Eielsen, KariAnne Vrabel, Asle Hoffart, Øyvind Rø, Jan H. Rosenvinge   +4 more
wiley   +1 more source

A Survey on the Integration of Blockchains and Databases. [PDF]

Data Sci Eng, 2023
Zhu C, Li J, Zhong Z, Yue C, Zhang M.
europepmc   +1 more source

Abstract unordered and ordered trees CRDT [PDF]

arXiv, 2012
Trees are fundamental data structure for many areas of computer science and system engineering. In this report, we show how to ensure eventual consistency of optimistically replicated trees. In optimistic replication, the different replicas of a distributed system are allowed to diverge but should eventually reach the same value if no more mutations ...
arxiv  

Single‐Cell and Spatial Transcriptomics Reveals a Stereoscopic Response of Rice Leaf Cells to Magnaporthe oryzae Infection

Advanced Science, EarlyView.
By employing a combination of single cell and spatial transcriptomic sequencing, this study presents a stereoscopic response of rice leaf to Magnaporthe oryzae infection. The vascular tissues mount defenses by producing phytoalexins. The immune strength is stronger toward the rice leaf tip than that of the leaf base.
Wei Wang, Xianyu Zhang, Yong Zhang, Zhe Zhang, Chang Yang, Wen Cao, Yuqin Liang, Qinzheng Zhou, Qian Hu, Yimai Zhang, Yu Wang, Yingying Xing, Wenfeng Qian, Nan Yao, Ning Xu, Jun Liu   +15 more
wiley   +1 more source