Results 101 to 110 of about 4,750,082 (287)
Ingeniería e Investigación, 2016 In this paper, a genetic algorithm (GA) based in an optimization approach is presented in order to search the optimum weighting matrix parameters of a linear quadratic regulator (LQR).
Mahesh Nagarkar, G. J. Vikhe Patil
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NLP Solutions as Asymptotic Values of ODE Trajectories
, 2014 In this paper, it is shown that the solutions of general differentiable constrained optimization problems can be viewed as asymptotic solutions to sets of Ordinary Differential Equations (ODEs).
Alamir, Mazen
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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Environmental Chemistry and SafetyAlthough tropical coral islands receive abundant annual precipitation, the heavy rainfall and the high porosity of coral sand lead to rapid rainwater loss, posing a severe challenge to water use, soil water retention, and plant growth.
Li Shen +5 more
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A Random-Key optimizer for combinatorial optimization [PDF]
Journal of Heuristics54 pages, 16 figures, 8 ...
Antonio A. Chaves +6 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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A Stray Current Sensor Based on an All-Side Cylindrical Spiral Fiber
IEEE Photonics Journal, 2017 In this paper, a stray current sensor based on an all-side cylindrical spiral fiber is proposed. The configuration of stray current sensor is illustrated first. The Jones matrix of sensor head is derived based on the geometric rotation effect. The output
Shao-Yi Xu +5 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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