Results 51 to 60 of about 4,750,082 (287)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

FORMATION AND OPTIMIZATION OF VARIOUS PORTFOLIOS MODELS ON THE VaR INDICATOR BASIS

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2017
This article describes a formation of various portfolios models based on H. Markovitz portfolio theory. The portfolios which can include instruments with fixed profitability and common stock are considered. As a risk measure VaR indicator is used.
Viktor Oliinyk, I. Bielova
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Adaptive Bound Optimization for Online Convex Optimization [PDF]

open access: yes, 2010
We introduce a new online convex optimization algorithm that adaptively chooses its regularization function based on the loss functions observed so far.
McMahan, H. Brendan, Streeter, Matthew
core   +1 more source

РОЗРОБКА МЕТОДУ ВИБОРУ ПРИСТРОЇВ КОМПЕНСАЦІЇ РЕАКТИВНОЇ ПОТУЖНОСТІ ЗА УМОВИ МІНІМАЛЬНИХ ЗВЕДЕНИХ ВИТРАТ

open access: yesElektrotehnìka ta Elektroenergetika, 2013
Розроблено метод оптимального вибору варіанта розподілу потужності пристроїв компенсації реактивної потужності за умови мінімальних зведених витрат, який дозволяє знизити втрати електроенергії у трансформаторах комплектних трансформаторних підстанцій ...
V. V. Popov, D. I. Komarichina
doaj   +1 more source

Genetic algorithms to determine the optimal parameters of an ensemble local mean decomposition

open access: yesActa Polytechnica, 2021
An optimization method for an ensemble local mean decomposition (ELMD) parameters selection using genetic algorithms is proposed. The execution of this technique depends heavily on the correct choice of the parameters of its model as pointed out in ...
Willian T. F. D. Silva   +1 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

THE IVESTIGATION OF LIQUID-MOVING SELF-FIRMING MIXTURE FOR STEEL CASTING FORMS IN ORDER TO OPTIMIZE ITS CONTENT

open access: yesAdvanced Engineering Research, 2010
The aim of the optimization of the liquid-moving self-firming mixture (LSM) content together with the regenerated sand for making steel shaped casting forms is discussed.
Y.A. ZINCHENKO
doaj  

Measuring the Optimality of Hadoop Optimization

open access: yesCoRR, 2013
In recent years, much research has focused on how to optimize Hadoop jobs. Their approaches are diverse, ranging from improving HDFS and Hadoop job scheduler to optimizing parameters in Hadoop configurations. Despite their success in improving the performance of Hadoop jobs, however, very little is known about the limit of their optimization ...
Woo-Cheol Kim   +2 more
openaire   +2 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

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