Results 161 to 170 of about 2,429,878 (317)
A Heuristic Approach to Portfolio Optimization [PDF]
Constraints on downside risk, measured by shortfall probability, expected shortfall, semi-variance etc., lead to optimal asset allocations which differ from the meanvariance optimum.
Evis Këllezi, Manfred Gilli
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
, 2014 This book of abstracts presents materials of the International Conference for Mathematical Modeling and Optimization in Mechanics (MMOM 2014) 6-7 March 2014, Jyväskylä, Finland.
International Conference for Mathematical Modeling and Optimization in Mechanics
core
Bilevel Optimization by Conditional Bayesian Optimization
Bilevel optimization problems have two decision-makers: a leader and a follower (sometimes more than one of either, or both). The leader must solve a constrained optimization problem in which some decisions are made by the follower. These problems are much harder to solve than those with a single decision-maker, and efficient optimal algorithms are ...
Vedat Dogan, Steven D. Prestwich
openaire +3 more sources
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
System Optimization Working Group Recommendations
University of Minnesota. System Optimization Working Group. (2025). System Optimization Working Group Recommendations.
University of Minnesota. System Optimization Working Group
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
A Systematic Taxonomy of the Sunflower Optimization Algorithm: Variants, Hybridization Strategies, Applications, and Research Directions. [PDF]
Biomimetics (Basel)Baştemur Kaya C.
europepmc +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Optimization of Risk Measures [PDF]
We consider optimization problems involving coherent risk measures. We derive necessary and sufficient conditions of optimality for these problems, and we discuss the nature of the nonanticipativity constraints.
Andrzej Ruszczynski, Alexander Shapiro
core