Results 81 to 90 of about 2,974,096 (303)
Optimizing Bayesian optimization
, 2018 We are concerned primarily with improving the practical applicability of Bayesian optimization. We make contributions in three key areas. We develop an intuitive online stopping criterion, allowing only as many steps as necessary to achieve the desired target to be taken. By combining this with intelligent online switching between acquisition functions
openaire +3 more sources
Stress-constrained topology optimization using the constrained natural element method [PDF]
This paper presents a topology optimization framework to achieve volume minimization with Crossland fatigue constraints under proportional loading using the Constrained Natural Element Method.
CHEN, Yanda +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Empipe™ User’s Manual Version 4.0 -- PC
, 1997 Empipe is a powerful and friendly software system for automated electromagnetic (EM) design optimization, driving the EM simulator em. Empipe allows you to designate geometrical and material parameters as candidate variables for optimization in an ...
Bandler, John W. +3 more
core +1 more source
Scientific ReportsHepatitis C virus (HCV) infection poses a significant public health challenge and often leads to long-term health complications and even death. Parkinson’s disease (PD) is a progressive neurodegenerative disorder with a proposed viral etiology.
Isis Narváez-Bandera +6 more
doaj +1 more source
Complex & Intelligent Systems, 2022 As a popular research in the field of artificial intelligence in the last 2 years, evolutionary neural architecture search (ENAS) compensates the disadvantage that the construction of convolutional neural network (CNN) relies heavily on the prior ...
Qingqing Liu +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Empipe™ User’s Manual Version 4.0 -- UNIX
, 1997 Empipe is a powerful and friendly software system for automated electromagnetic (EM) design optimization, driving the EM simulator em. Empipe allows you to designate geometrical and material parameters as candidate variables for optimization in an ...
Bandler, John W. +3 more
core +1 more source
Equating κ Maximum Degrees in Graphs without Short Cycles
Discussiones Mathematicae Graph Theory, 2020 For an integer k at least 2, and a graph G, let fk(G) be the minimum cardinality of a set X of vertices of G such that G − X has either k vertices of maximum degree or order less than k.
Fürst Maximilian +4 more
doaj +1 more source
IEEE Access, 2020 In recent decades, moisture evaluation of transformer oil-immersed cellulose insulation has been widely studied by using the frequency domain spectroscopy (FDS) technique.
Jiefeng Liu +4 more
doaj +1 more source