Results 71 to 80 of about 2,985,285 (303)
Stress-constrained topology optimization using the constrained natural element method [PDF]
This paper presents a topology optimization framework to achieve volume minimization with Crossland fatigue constraints under proportional loading using the Constrained Natural Element Method.
CHEN, Yanda +4 more
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Optimizing Bayesian optimization
We are concerned primarily with improving the practical applicability of Bayesian optimization. We make contributions in three key areas. We develop an intuitive online stopping criterion, allowing only as many steps as necessary to achieve the desired target to be taken. By combining this with intelligent online switching between acquisition functions
openaire +3 more sources
Empipe™ User’s Manual Version 4.0 -- PC
Empipe is a powerful and friendly software system for automated electromagnetic (EM) design optimization, driving the EM simulator em. Empipe allows you to designate geometrical and material parameters as candidate variables for optimization in an ...
Bandler, John W. +3 more
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Hepatitis C virus (HCV) infection poses a significant public health challenge and often leads to long-term health complications and even death. Parkinson’s disease (PD) is a progressive neurodegenerative disorder with a proposed viral etiology.
Isis Narváez-Bandera +6 more
doaj +1 more source
Frequency domain spectroscopy (FDS) technique is widely applied in the condition assessment of the oil-paper system in power transformers. However, the synergistic effect generated by moisture and temperature on the FDS data cannot be analyzed by the ...
Xianhao Fan +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Empipe™ User’s Manual Version 4.0 -- UNIX
Empipe is a powerful and friendly software system for automated electromagnetic (EM) design optimization, driving the EM simulator em. Empipe allows you to designate geometrical and material parameters as candidate variables for optimization in an ...
Bandler, John W. +3 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Optimization Algorithms - Classics and Last Advances is devoted to developing algorithm theory and exploring the use of different optimization algorithms for solving various problems in pure science, applied physics, and information technology.
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Most research and development projects require the optimization of a system response as a function of several experimental factors. Familiar chemical examples are the maximization of product yield as a function of reaction time and temperature; the maximization of analytical sensitivity of a wet chemical method as a function of reactant concentration ...
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