Results 221 to 230 of about 9,308,983 (309)
ABSTRACT This study assessed whether continued treatment with anti‐CGRP monoclonal antibodies (mAbs) is driven more by reductions in monthly migraine days (MMDs) or patients' global impression of change (PGIC), a patient‐reported outcome. Among 169 patients treated with anti‐CGRP mAbs, 21.3% discontinued due to ineffectiveness. PGIC responders (≥ 5) at
Marina Romozzi+4 more
wiley +1 more source
Inverse-design topology optimization of magnonic devices using level-set method. [PDF]
Voronov AA+5 more
europepmc +1 more source
CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu+12 more
wiley +1 more source
Mine fire emergency path planning based on hybrid strategy improved WOA algorithm. [PDF]
Qi Y, Yu K, Li X, Wang W, Cui X, Bai C.
europepmc +1 more source
Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao+4 more
wiley +1 more source
Bio-Inspired Observability Enhancement Method for UAV Target Localization and Sensor Bias Estimation with Bearing-Only Measurement. [PDF]
Wang Q, Li Z, Peng J, Lu K.
europepmc +1 more source
ABSTRACT Dopaminergic medication and deep brain stimulation (DBS) improve motor symptoms in Parkinson's disease (PD), but levodopa response alone may not predict DBS outcomes. We retrospectively analyzed 19 PD patients undergoing levodopa challenges with and without prior transcranial direct current stimulation targeting a defined PD response network ...
Lukas L. Goede+3 more
wiley +1 more source
Utility-based optimization of Fujikawa's basket trial design - Pre-specified protocol of a comparison study. [PDF]
Sauer LD, Ritz A, Kieser M.
europepmc +1 more source