Results 161 to 170 of about 2,985,285 (303)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

An Efficient Gradient-Free Topology Optimization Method Based on Superellipse Curves and a Multilayer Perceptron Surrogate. [PDF]

Micromachines (Basel)
Jin F, Liu Y.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Metaheuristic-driven automatic ARIMA order selection using spider monkey optimization for agricultural production forecasting. [PDF]

MethodsX
Kumar A, H RPC, P FK, Rathod S, Shankar SV, Ray M, B SAS, Patil S, Mazumder C, Mishra SK, Lavanya V, Misra AK, Choudhary VK.   +12 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Discrete optimization. proceedings of the Advanced Research Institute on Discrete Optimization and Systems Applications of the Systems Science Panel of NATO and of the Discrete Optimization Symposium, co-sponsored by IBM Canada and SIAM, Banff, Alta. and Vancouver, B.C., Canada, August 1977 /

, 1979
Includes bibliographical references.Print version record.Cover; TOCContents; Part 3: Methodology; Section 1: Surveys; CHChapter 1. Disjunctive programming; CHChapter 2. Methods of nonlinear 0-1 programming; CHChapter 3.
IBM Canada., Society for Industrial and Applied Mathematics., Hammer, P. L.,1936-2006., Korte, B. H.(Bernhard H.),, Discrete Optimization Symposium(1977 :Vancouver, B.C.), Advanced Research Institute on Discrete Optimization and Systems Applications(1977 :Banff, Alta.), North Atlantic Treaty Organization.Systems Science Panel., Johnson, E. L.(Ellis L.)   +7 more
core  

A hybrid deep learning framework for automated treatment planning in cervical cancer radiotherapy. [PDF]

J Appl Clin Med Phys
Jiang H, Yuan Z, Liu Z, Wang Y, Hu W, Yan B, Yang Y.   +6 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Dosimetric evaluation of systematic source position uncertainty along the source path and robust planning during MRI-only cervical HDR brachytherapy. [PDF]

J Appl Clin Med Phys
Singh A, Karshafian R, Ravi A, Paudel MR.   +3 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source