Results 71 to 80 of about 2,403,125 (249)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Automatic detection and classification of lung cancer CT scans based on deep learning and ebola optimization search algorithm

, 2023
Tehnan I. A. Mohamed, Olaide N. Oyelade, Absalom E. Ezugwu   +2 more
openalex   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Topology optimization with implicit functions and regularization [PDF]

, 2003
Ted Belytschko, Shaoping Xiao, Chandu Parimi   +2 more
openalex   +1 more source

Grid-connected hybrid renewable energy systems for supermarkets with electric vehicle charging platforms: Optimization and sensitivity analyses

, 2023
A. Allouhi, Shafiqur Rehman
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

ePyDGGA: automatic configuration for fitting epidemic curves

Scientific Reports
Many epidemiological models and algorithms are used to fit the parameters of a given epidemic curve. On many occasions, fitting algorithms are interleaved with the actual epidemic models, which yields combinations of model-parameters that are hard to ...
Josep Alòs, Carlos Ansótegui, Ivan Dotu, Manuel García-Herranz, Pol Pastells, Eduard Torres   +5 more
doaj   +1 more source

Enhanced Land Use and Land Cover Classification Through Human Group-based Particle Swarm Optimization-Ant Colony Optimization Integration with Convolutional Neural Network [PDF]

, 2023
Moresh Mukhedkar, Chamandeep Kaur, D. Srinivasa Rao, Shweta Bandhekar, Mohammed Saleh Al Ansari, Maganti Syamala, Yousef A. Baker El–Ebiary   +6 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Securing federated learning: a defense strategy against targeted data poisoning attack

Discover Internet of Things
Ensuring the security and integrity of Federated Learning (FL) models against adversarial attacks is critical. Among these threats, targeted data poisoning attacks, particularly label flipping, pose a significant challenge by undermining model accuracy ...
Ansam Khraisat, Ammar Alazab, Moutaz Alazab, Tony Jan, Sarabjot Singh, Md. Ashraf Uddin   +5 more
doaj   +1 more source