Results 71 to 80 of about 4,697,654 (286)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Joint Optimal Power Allocation and Relay Selection Scheme in Energy Harvesting Two-Way Relaying Network

Future Internet, 2019
In this paper, we propose a joint power allocation, time switching (TS) factor and relay selection scheme for an energy harvesting two-way relaying communication network (TWRN), where two transceivers exchange information with the help of a wireless ...
Xin Song, Siyang Xu, Zhigang Xie, Xiuwei Han   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Use of Plackett–Burman Statistical Design to Study Factors Acting on the Nitric Acid Leaching of Rare Earth Elements from Moroccan Phosphogypsum

Journal of Chemistry
This work is an attempt to understand and optimize the rare earth elements leaching from Moroccan phosphogypsum using a nitric acid solution. The Plackett–Burman statistical design was used to identify the statistically significant factors responsible ...
Fatima Asafar, Marouane Amine, Abdelkader Outzourhit, Latifa Bilali, Mehdi Nadifiyine   +4 more
doaj   +1 more source

Set optimization - a rather short introduction

, 2014
Recent developments in set optimization are surveyed and extended including various set relations as well as fundamental constructions of a convex analysis for set- and vector-valued functions, and duality for set optimization problems.
A Ben-Tal, A Göpfert, A Götz, A Löhne, A Löhne, A Löhne, A Löhne, A Löhne, A Roux, AA Lechicki, AH Hamel, AH Hamel, AH Hamel, AH Hamel, AH Hamel, AH Hamel, AH Hamel, AH Hamel, AM Rubinov, AY Azimov, AY Azimov, B Fuchssteiner, BM Glover, BN Pshenichnyi, BS Mordukhovich, BS Mordukhovich, BS Mordukhovich, BS Mordukhovich, C Brink, C Gerth (Tammer), C Gutiérrez, C Malivert, C Zălinescu, C Zălinescu, CS Lalitha, D Denneberg, D Gourion, D Gourion, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, D Kuroiwa, DG Luenberger, DG Luenberger, DT Luc, DT Luc, DT Luc, DT Luc, E Hernández, E Hernández, E Hernández, E Hernández, E Hernández, E Jouini, E Klein, E Muselli, E Szpilrajn, F Ferro, F Ferro, F Flores-Bazán, F Flores-Bazán, F Heyde, F Heyde, F Heyde, F Heyde, F Heyde, F Heyde, G Godini, G Pollák, GP Crespi, GP Crespi, GP Crespi, GY Chen, GY Chen, GY Chen, H Isermann, H Joe, H Kawasaki, HP Benson, HP Benson, HW Corley, HW Corley, I Singer, J Baier, J Benoist, J Getán, J Jahn, J Jahn, J Jahn, J Jahn, J Olko, J Zowe, J Zowe, J Zowe, J-E Martínez-Legaz, J-P Aubin, JM Borwein, JM Borwein, JM Borwein, JM Borwein, JP Dauer, JP Dauer, JP Dauer, JSH Kornbluth, JW Nieuwenhuis, K Keimel, K Nehring, K-H Elster, K-U Jahn, KD Schmidt, L Hernández, L Rodríguez-Marín, L-J Lin, M Alonso, M Durea, M Ehrgott, M Maggis, M Volle, M Ward, M Ward, M Ward, MM Day, N Galatos, NB Minh, NB Minh, P Artzner, P Prakash, P Walley, PC Fishburn, PH Dien, PH Sach, R Cross, RC Young, RI Boţ, RI Boţ, RP Dilworth, RT Rockafellar, RT Rockafellar, RT Rockafellar, RW Shephard, S Dolecki, S Gaubert, S Nishizawa, S Nishizawa, S Nishizawa, SJ Li, SJ Li, SL Brumelle, SL Brumelle, SS Kutateladze, SS Wang, T Maeda, T Maeda, T Pennanen, T Tanino, T Tanino, T Tanino, T Tanino, TS Blyth, TXD Ha, TXD Ha, TXD Ha, U Zimmermann, V Postolică, V Postolică, VV Beresnev, VV Gorokhovik, W Bossert, W Oettli, W Rödder, W Schachermayer, W Song, W Song, W Song, WW Breckner, WY Zhang, XQ Yang, XQ Yang, Y Araya, Y Kannai, Y Sawaragi, YM Kabanov, YM Liu, Z Li, Z-F Li, ZG Nishianidze   +192 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A modified migration model biogeography evolutionary approach for electromagnetic device multiobjective optimization [PDF]

, 2014
Inthispaper, we present anefficient androbust algorithm for multiobjective optimization of electromagnetic devices.Therecentlydeveloped biogeography-based optimization (BBO) is modified byadapting its migration model function so as to improve its ...
Dupré, Luc, Mohamed Abouelyazied Abdallh, Ahmed, Sayed, Mahmoud   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source