Results 101 to 110 of about 953,075 (309)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Research on Optimization of Diesel Engine Speed Control Based on UKF-Filtered Data and PSO Fuzzy PID Control

open access: yes
With the continuous development of industrial automation, diesel engines play an increasingly important role in various types of construction machinery and power generation equipment.
Luchen Lin   +5 more
core   +1 more source

Robust fluid control of multiclass queuing networks [PDF]

open access: yes, 2006
Thesis (S.M.)--Massachusetts Institute of Technology, Computation for Design and Optimization Program, 2006.Includes bibliographical references (p. 89-92).This thesis applies recent advances in the field of robust optimization to the optimal control of ...
Su, Hua, S.M. Massachusetts Institute of Technology
core  

Parallel Solution of Robust Nonlinear Model Predictive Control Problems in Batch Crystallization

open access: yes, 2016
Representing the uncertainties with a set of scenarios, the optimization problem resulting from a robust nonlinear model predictive control (NMPC) strategy at each sampling instance can be viewed as a large-scale stochastic program.
Yankai Cao   +3 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Quality-Related Fault Detection Based on Improved Independent Component Regression for Non-Gaussian Processes

open access: yesIEEE Access, 2019
Partial least squares (PLS) and linear regression methods have been widely utilized for quality-related fault detection in industrial processes recently.
Majed Aljunaid, Hongbo Shi, Yang Tao
doaj   +1 more source

A PSO-Based Recurrent Closed-Loop Optimization Method for Multiple Controller Single-Output Thermal Engineering Systems

open access: yes, 2019
For solving the problems of closed-loop optimization on controller parameters of multiple-controller single-output thermal engineering system, this paper proposes a recurrent optimization method that is based on the particle swarm computing and closed ...
Lei Pan, Xingjian Liu
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Launcher attitude control: some additional design and optimization tools [PDF]

open access: yes, 2003
This paper deals with the launcher attitude control during atmospheric flight. A two step approach combining an H1 control design and an optimization procedure is proposed.
Clément, Benoît   +3 more
core  

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