Results 61 to 70 of about 654,792 (268)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Smartphone-Based 3D Indoor Pedestrian Positioning through Multi-Modal Data Fusion

Sensors, 2019
Combining research areas of biomechanics and pedestrian dead reckoning (PDR) provides a very promising way for pedestrian positioning in environments where Global Positioning System (GPS) signals are degraded or unavailable.
Hongyu Zhao, Wanli Cheng, Ning Yang, Sen Qiu, Zhelong Wang, Jianjun Wang   +5 more
doaj   +1 more source

Leapfrog for Optimal Control

SIAM Journal on Numerical Analysis, 2008
The leapfrog algorithm, so called because of its geometric nature, for solving a class of optimal control problems is proposed. Initially a feasible trajectory is given and subdivided into smaller pieces. In each subdivision, with the assumption that local optimal controls can easily be calculated, a piecewise-optimal trajectory is obtained.
C. Yalçin Kaya, Lyle Noakes
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Flow-dynamics informed Kolmogorov–Arnold networks for simulating subsonic compressible flow around airfoils [PDF]

AIP Advances
Deep learning has been probed for surrogate modeling of flow around airfoils. While physics-informed neural networks (PINNs) built on sparse data possess some physical interpretability, the prediction of flow fields may deviate from the true distribution.
Jianren Sun, Zhongyang Fei, Pan Qin
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Quality Weakly Related Fault Detection Based on Weighted Dual-Step Feature Extraction

IEEE Access, 2019
Process variables can be separated into quality strongly related variables (QSRVs) and quality weakly related variables (QWRVs) based on the difference of correlation between process variables and quality.
Bo Zhao, Hongbo Shi, Bing Song, Shuai Tan   +3 more
doaj   +1 more source

Potential-Based Differential Evolution Algorithm With Joint Adaptation of Parameters and Strategies

IEEE Access, 2020
In the differential evolution (DE) algorithm, numerous studies have independently performed strategy adaptation and parameter adaptation. However, the strategy and parameters are interrelated in their impact on algorithm performance.
Li Tian, Zhichao Li, Xuefeng Yan
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source