ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos +9 more
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Research on the optimization design of gradient ceramic cutting tools based on thermomechanical coupling mechanism. [PDF]
Zhu G, Wang G, He X.
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ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
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Optimization Design and Mechanical Performance Study of Carbon Fiber-Reinforced Composite Load-Carrying Structures for Subway Driver Cabin. [PDF]
Wang J, Yang B, Tian H, Wang W, Sang X.
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Outdoor thermal comfort benchmarks and optimization design for children in open parks of hot summer and cold winter region. [PDF]
Luyao H, Ling L, Xinkai L, Junfeng D.
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Optimization Design and SLM Manufacturing of Porous Titanium Alloy Femoral Stem. [PDF]
Zhao L, Wang Y, Wang Q, Zhang Y, Yang G.
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Integrated diagnosis optimization design of the electronic equipment based on spatial mapping. [PDF]
Gu XP, Shi XJ.
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Optimization Design of Key Mechanical Properties of Cement-Based Thin Spray-On Liners for Monorail Transport Systems in High-Water-Seepage Areas of Coal Mines. [PDF]
Zhu S, Zhao B, Li C.
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Optimization design of centrifugal impeller based on Bezier surface and FFD space grid parameterization. [PDF]
Wang Y, Sun Z, Liu J, Liu M, Zhou Y.
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Design is as Easy as Optimization
SIAM Journal on Discrete Mathematics, 2006We consider the class of max-min and min-max optimization problems subject to a global budget constraint. We undertake a systematic algorithmic and complexity-theoretic study of such problems, which we call design problems. Every optimization problem leads to a natural design problem. Our main result uses techniques of Freund and Schapire [Games Econom.
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