Results 111 to 120 of about 808,313 (268)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Search engine Performance optimization: methods and techniques. [PDF]
F1000Res, 2023 Aman SS, N'guessan BG, Agbo DDA, Kone T.
europepmc +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Application of Parameter Optimization Methods Based on Kalman Formula to the Soil-Crop System Model. [PDF]
Int J Environ Res Public Health, 2023 Guo Q, Wu W.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Group optimization methods for dose planning in tES. [PDF]
J Neural EngSalvador R, Zhou J, Manor B, Ruffini G.
europepmc +2 more sources
A Stable Large-Scale Multiobjective Optimization Algorithm with Two Alternative Optimization Methods. [PDF]
Entropy (Basel), 2023 Liu T, Zhu J, Cao L.
europepmc +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Application of Multi-Criteria Optimization Methods in the Calibration Process of Digital Measuring Instruments. [PDF]
Sensors (Basel), 2023 Klebba M, Adamczyk A, Wąż M, Iwen D.
europepmc +1 more source