Serine Protease HtrA2 from Halophilic Archeon <i>Haloarcula</i> sp. TG1: Heterologous Expression, Characterization and Immobilization. [PDF]
Kurt-Kızıldoğan A +5 more
europepmc +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Diversity, Pathogenicity, and Biological Characteristics of Root Rot Pathogens from Lycium barbarum L. in Qinghai Province, China. [PDF]
Zhao Y +5 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Optimization of Multi-gravity Separator (MGS) Parameters for Specularite Ore Beneficiation: Evaluating Box-Behnken and Central Composite Designs. [PDF]
Çerik Ç, Şen S.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Phosphorus deficiency and its availability in excess affect physio-biochemical performance, yield potential, seed vigor, and grain quality of rice influenced by Pup1 QTL. [PDF]
S TS +7 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Multi-Criteria Optimization of Microwave-Cured Pineapple Leaf Fiber/LDPE Biocomposites for Enhanced Mechanical Performance. [PDF]
Saha M +5 more
europepmc +1 more source

