Results 31 to 40 of about 648 (252)
Adopting the Euro: Costs or Benefits? [PDF]
Theoretical and Applied Economics, 2007 This paper evaluates the present estate of euro implementation in Monetary and Economic Union (EMU). The Romanian admittance in EU at January 2007 increases interest to study the transmission and coordination mechanisms, related to mix common monetary ...
Cristian Socol, Aura Socol
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Optimum Currency Areas Theory: An Empirical Application to Turkey [PDF]
South East European Journal of Economics and Business, 2007 This study aims to assess Turkey's position relative to European countries with respect to the optimum currency areas (OCA) criteria, taking Germany as the center country and employing Mahalanobis distance as a similarity measure. To this end, we followed a novel approach in the application of Hodrick-Prescott and Baxter-King filters to the industrial ...
Itir Ozer, Ibrahim Ozkan, Okan Aktan
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
ESTIMATING THE BUSINESS CYCLE SYNCHRONIZATION BETWEEN ROMANIA AND THE EURO AREA [PDF]
Business Excellence and Management, 2016 The conditions of the well-functioning of a monetary union were defined by the optimum currency area theory. From this perspective, the business cycles synchronization outlined itself as a meta-condition for the benefits of sharing a common currency to ...
Dan IVĂNESCU , Laura IVĂNESCU
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CONSIDERATION RELATING THE THEORETICAL AND PRACTICAL FRAMEWORK OF THE MONETARY UNION [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2018 For the first time in economic theory, the canadian economist Robert Mundel (1961) signaled the fact that countries with close trade links and with similar economic cycles could benefit major advantages using a common currency by reducing transaction ...
MERCEA (HANDRO) PATRICIA AMALIA
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source