Results 41 to 50 of about 2,538 (294)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Optimum currency areas: a policy view
PSL Quarterly Review, 2006 Article originally published in the volume 59 issue 239 of Banca Nazionale del Lavoro Quarterly Review (also known as BNL Quarterly Review).
Filippo Cesarano
doaj
An Optimum Currency Crisis [PDF]
The European Journal of Comparative Economics, 2014 This paper presents an ex-post assessment of the current situation of the EMU in light of the conditions prescribed by the theory of Optimum Currency Areas (OCA). The analysis shows that some of those conditions were satisfied at the inception of the EMU,
Paolo Pasimeni
doaj
Demand and supply shock symmetry across Polish voivodeships
Studia Regionalne i Lokalne, 2018 The aim of this paper is to evaluate the symmetry of demand and supply shocks affecting Polish voivodeships and to assess the risk of asymmetric shocks in the future. The study employs the SVAR-based Blanchard and Quah (1989) decomposition as modified by
Paweł Gajewski
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The equilibrium approach to optimum currency areas
PSL Quarterly Review, 2006 Article originally published in the volume 59 issue 237 of Banca Nazionale del Lavoro Quarterly Review (also known as BNL Quarterly Review).
Filippo Cesarano
doaj
EСONOMIC AND MONETARY UNION: CORRECTION ОF FAILURES
Vestnik MGIMO-Universiteta, 2013 The articles deals with the initial design failures of the European and Monetary Union which could have lead to the current sovereign debt crisis of some of its member-states.
A. N. Tsibulina
doaj +1 more source
Lezioni dall’eurozona per l’Africa (Lessons for Africa from the Eurozone)
Moneta e Credito, 2020 La recente crisi dell’eurozona, insieme all’annunciata riforma del Il susseguirsi di crisi nella zona euro rende forse necessaria una riconsiderazione dei progetti di unione monetaria in Africa.
Paul R. Masson
doaj +1 more source